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Table 5 (Abstract P61).

From: 31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part one

  Pre-Treatment Blood-Based Post-Treatment Blood-Based
  16-Gene mRNA Signature 8-Gene mRNA Signature
Melanoma Training Test Test Training Test Test
Cases N=210 N=150 N=150 N=210 N=150 N=150
Biomarker Response Response Survival Response Response Survival
Sensitivity 96.4% 65.0% 74.4% 85.7% 70.0% 69.8%
Specificity 66.5% 59.2% 55.1% 64.3% 60.8% 59.8%
NPV 99.2% 91.7% 84.3% 96.7% 92.9% 83.1%
AUC 0.8634 0.6376 0.6785 0.7853 0.6125 0.6512