Fig. 2

Association between TIS scores and mutation load. a TIS score plotted against log2 mutation within each tumor type. b Point estimates and 95% confidence intervals for the correlation between TIS score and log2 mutation load within each tumor type. Box size represents the precision of the estimate with larger boxes indicating smaller standard errors; horizontal lines represent 95% confidence intervals. c Interquartile range of TIS score and mutation load in each cancer type. To place cancer types in context, a line connects SKCM to the origin